Invitrx Amniotic Tissue

330-459-8000

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Invitrx Amniotic Tissue

Invitra AT is a biological acellular product derived from human amnion.  The amniotic tissue is comprised of an extracellular matrix that forms a natural scaffold. The amniotic tissue has a series of anti-inflammatory, anti-bacterial, anti-viral properties as well as low immunogenicity.(1,2)   This natural scaffold works as a physical barrier that can contain cells to an affected area by maintaining adhesion of cells.(3)

 

  1. Akinbi, H. T., Narendran, V., Pass, A. K., Markart, P., & Hoath, S. B. (2004). Host defense proteins in vernix caseosa and amniotic fluid. American journal of obstetrics and gynecology, 191(6), 2090-2096.

  2. Espinoza, J., Chaiworapongsa, T., Romero, R., Edwin, S., Rathnasabapathy, C., Gomez, R., … & Blackwell, S. (2003). Antimicrobial peptides in amniotic fluid: defensins, calprotectin and bacterial/permeability-increasing protein in patients with microbial invasion of the amniotic cavity, intra-amniotic inflammation, preterm labor and premature rupture of membranes. The Journal of Maternal-Fetal & Neonatal Medicine, 13(1), 2-21.

  3. Mamede, A. C., Carvalho, M. J., Abrantes, A. M., Laranjo, M., Maia, C. J., & Botelho, M. F. (2012). Amniotic membrane: from structure and functions to clinical applications. Cell and tissue research, 349(2), 447-458. \

 

All of our donors are pre-screened through medical record review and evaluation of prenatal tests. Eligibility is confirmed through behavior risk assessment, physical assessment, donor medical history, review of blood test results, and communicable disease testing.  Invitra Amniotic AT is a Human Cellular and Tissue-Based Products (HCT/P) as defined by US FDA 21 C.F.R. § 1271 and is intended for homologous use only as determined by a physician.

 

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